Abstract: The integration of Artificial Intelligence (AI) into medical imaging represents a transformative shift in healthcare, offering significant improvements in diagnostic accuracy, efficiency, and patient outcomes. This paper explores the application of AI technologies in the analysis of medical images, focusing on techniques such as convolutional neural networks (CNNs) and deep learning models. We discuss how these technologies are applied to various imaging modalities, including X-rays, MRIs, and CT scans, to enhance disease detection, image segmentation, and diagnostic support. Additionally, the (...) paper addresses the challenges faced in AI-driven medical imaging, including data quality, model interpretability, and ethical considerations. By examining recent advancements and real-world case studies, this paper provides insights into the current state of AI in medical imaging and its potential future directions. The findings highlight the ongoing evolution of AI technologies and their crucial role in advancing medical diagnostics and treatment strategies. (shrink)

This article explores the philosophical concept of akrasia, also known as weakness of will, and demonstrates its relevance to clinical practice. In particular, it challenges an implicit notion of control over one’s actions that might impede recovery from substance misuse. Reflecting on three fictional case vignettes, we show how philosophical work on akrasia helps avoid this potentially harmful notion of control by supporting a holistic engagement with people for whom substance misuse is a problem. We argue that such engagement enhances (...) their prospects of recovery by focusing on agency over time, as opposed to individual lapses. (shrink)

Deep learning may transform health care, but model development has largely been dependent on availability of advanced technical expertise. The aim of this study is to develop a deep learning model to predict the gender from retinal fundus images. The proposed model was based on the Xception pre-trained model. The proposed model was trained on 20,000 retinal fundus images from Kaggle depository. The dataset was preprocessed them split into three datasets (training, validation, Testing). After training and cross-validating the proposed model, (...) it was evaluated using the testing dataset. The result of testing, the area under receiver operating characteristic curve (AUROC) of the model was 0.99, precision, recall, f1-score and accuracy were 99%, precision, recall, f1-score and accuracy were 96.83%, 96.83%, 96.82% and 96.83% respectively.. Clinicians are presently unaware of dissimilar retinal feature variants between females and males, stressing the importance of model explain ability for the prediction of gender from retinal fundus images. The proposed deep learning may enable clinician-driven automated discovery of novel visions and disease biomarkers. (shrink)

According to the literature review, there is much room for improvement of college student retention. The aim of this research is to evaluate the possibility of using deep and machine learning algorithms to predict whether students continue to attend college or will stop attending college. In this research a feature assessment is done on the dataset available from Kaggle depository. The performance of 20 learning supervised machine learning algorithms and one deep learning algorithm is evaluated. The algorithms are trained using (...) 11 features from 1000 records of previous student registrations that have been enrolled in college. The best performing classifier after tuning the parameters was NuSVC. It achieved Accuracy (91.00%), Precision (91.00%), Recall (91.00%), F1-score (91.00%), and time required for training and testing (0.04 second). Additionally, the proposed DL algorithm scored: Accuracy (93.00%), Precision (93.00%), Recall (93.00%), F1-score (93.00%), time required for training and testing (0.66 second) for predicting whether student will continue to attend college or not. (shrink)

In December 2013, the Nonhuman Rights Project (NhRP) filed a petition for a common law writ of habeas corpus in the New York State Supreme Court on behalf of Tommy, a chimpanzee living alone in a cage in a shed in rural New York (Barlow, 2017). Under animal welfare laws, Tommy’s owners, the Laverys, were doing nothing illegal by keeping him in those conditions. Nonetheless, the NhRP argued that given the cognitive, social, and emotional capacities of chimpanzees, Tommy’s confinement constituted (...) a profound wrong that demanded remedy by the courts. Soon thereafter, the NhRP filed habeas corpus petitions on behalf of Kiko, another chimpanzee housed alone in Niagara Falls, and Hercules and Leo, two chimpanzees held in research facilities at Stony Brook University. Thus began the legal struggle to move these chimpanzees from captivity to a sanctuary, an effort that has led the NhRP to argue in multiple courts before multiple judges. The central point of contention has been whether Tommy, Kiko, Hercules, and Leo have legal rights. To date, no judge has been willing to issue a writ of habeas corpus on their behalf. Such a ruling would mean that these chimpanzees have rights that confinement might violate. Instead, the judges have argued that chimpanzees cannot be bearers of legal rights because they are not, and cannot be persons. In this book we argue that chimpanzees are persons because they are autonomous. (shrink)

Abstract: The rapid advancement of artificial intelligence (AI) has catalyzed significant developments in autonomous systems, which are increasingly shaping diverse sectors including transportation, robotics, and industrial automation. This paper explores the evolution of AI technologies that underpin these autonomous systems, focusing on their capabilities, applications, and the challenges they present. Key areas of discussion include the technological innovations driving autonomy, such as machine learning algorithms and sensor integration, and the practical implementations observed in autonomous vehicles, drones, and robotic systems. Additionally, (...) the paper addresses critical challenges including safety, ethical concerns, and regulatory issues that influence the deployment and acceptance of autonomous technologies. By examining current trends and future prospects, this research aims to provide a comprehensive overview of how AI is transforming the landscape of autonomous systems and to identify key areas for future research and development. (shrink)

The issue of safety culture is one of the most important in a modern medical facility because any problems during the provision of services may lead to irreversible consequences. Not only the patient may suffer, but the doctor who assisted. Unfortunately, very little attention to this issue is paid in Ukraine. Based on this, we can say that the topic is relevant and requires studying. -/- The purpose of writing this article is the analysis of the ways of forming professional (...) safety culture in clinical medicine. The methods by which we carried out scientific research are observation, analysis, evaluation, comparison, generalization. -/- The work examined interpretation of the term "safety culture", types of innovation in which it belongs and the main methods of its creation in the medical field. -/- Safety culture in the medical field involves the right of all health care workers to use measures to prevent actions that can harm a patient or a colleague. Different approaches were considered in the interpretation of the term "safety culture" and we proposed our own: safety culture is a system of values, objectives, knowledge and skills, rules and procedures, convictions shared by representatives of a certain medical profession and supported by patients, creating a favourable working climate, atmosphere of trust and becoming an efficient tool for achieving the goals of the organization. -/- The main components of the safety culture were defined: responsibilities of managers, communication, performance, resources of safety, trust, the degree of job satisfaction, etc. Based on several studies, it was found that no country has a perfect medical system. Every system should be improved. -/- We proposed measures to fix the situation with the safety culture in health care facilities. The correct management of safety can eliminate or fix many medical errors. That is why the need for a clear program of implementation, execution and control of SC in the medical establishment is necessary. -/- Scientific novelty of this work lies in the interpretation of the term "safety culture" at medical institutions and in determining major steps towards its creation. Practical value of the work is the opportunity to implement these steps in medical institutions for improvement of the safety culture and, therefore, to reduce the risk of bad accidents during treatment. -/- Further research can address safety culture management in medical institutions on the examples from the experience of countries with effective systems of health care. (shrink)

A study was carried out from October, 2020 to September, 2021to investigate the diversity of fishes and the conservation status of Chittaura Jheel (Bahraich), Uttar Pradesh. During the study period, 38 fish species belonging to 28 genera, 14 families and 7 orders have been identified. The order Cypriniformes was found the dominated order with 15 species(39.47%) followed by Siluriformes 10 species (26.31%), Perciformes 4 species (10.52%), Ophiocephaliformes 4 species (10.52%), Synbranchiformes2 species (5.26%), Osteoglossiformes 2 species (5.26%) and Clupiformes 1 species (...) (2.63 %), The present investigation showed that the wetland, Chittaura Jheel possesses rich fish biodiversity but proper conservation measures are required to maintain sustainability and richness of the fish species diversity of that wetland of U.P. According to IUCN, 30 were enlisted as Least Concern (LC), 2 species as near endangered (NE), 3 species as near threatened (NT), 2 listed as Endangered (EN) and 1 species was listed as Vulnerable (VU). There is a need of conservation of fish diversity of this natural wetland. The pressure is increasing day by day due to increasing population, leading to loss of fish diversity hence identifying the problem and making a better management plan is the way for conservation of the fish diversity of the Chittaura Jheel, a wetland of Bahraich district of Uttar Pradesh. (shrink)

Purpose – To review and discuss Luciano Floridi’s 2019 book The Logic of Information: A Theory of Philosophy as Conceptual Design, the latest instalment in his philosophy of information (PI) tetralogy, particularly with respect to its implications for library and information studies (LIS). Design/methodology/approach – Nine scholars with research interests in philosophy and LIS read and responded to the book, raising critical and heuristic questions in the spirit of scholarly dialogue. Floridi responded to these questions. Findings – Floridi’s PI, including (...) this latest publication, is of interest to LIS scholars, and much insight can be gained by exploring this connection. It seems also that LIS has the potential to contribute to PI’s further development in some respects. Research implications – Floridi’s PI work is technical philosophy for which many LIS scholars do not have the training or patience to engage with, yet doing so is rewarding. This suggests a role for translational work between philosophy and LIS. Originality/value – The book symposium format, not yet seen in LIS, provides forum for sustained, multifaceted and generative dialogue around ideas. (shrink)

Shortages of new therapeutics to treat coronavirus disease (COVID-19) have forced clinicians, public health officials, and health systems to grapple with difficult questions about how to fairly allocate potentially life-saving treatments when there are not enough for all patients in need (1). Shortages have occurred with remdesivir, tocilizumab, monoclonal antibodies, and the oral antiviral Paxlovid (2) -/- Ensuring equitable allocation is especially important in light of the disproportionate burden experienced during the COVID-19 pandemic by disadvantaged groups, including Black, Hispanic/Latino and (...) Indigenous communities, individuals with certain disabilities, and low-income persons. However, many health systems have resorted to first-come, first-served approaches to allocation, which tend to disadvantage individuals with barriers in access to care (3). There is mounting evidence of racial, ethnic, and socioeconomic disparities in access to medications for COVID-19 (4, 5). -/- One potential method to promote equitable allocation is to use a weighted lottery, which is an allocation strategy that gives all eligible patients a chance to receive the scarce treatment while also allowing the assignment of higher or lower chances according to other ethical considerations (6). We sought to assess the feasibility of implementing a weighted lottery to allocate scarce COVID-19 medications in a large U.S. health system and to determine whether the weighted lottery promotes equitable allocation. (shrink)

The present study was an attempt to access and evaluate the status and distribution of waders associated to wetlands of Ujani Reservoir with special reference to north - west region. Waders are the birds generally observed along shorelines and mudflats that wade in order to forage for food in mud or sand. Ujani wetlands provide feeding and roosting grounds for resident and migratory waders. This study was conducted from December 2015 to November 2017 including seasonal visits to five wetland sites (...) i.e. Kumbhargaon, Diksal, Kondhar-Chincholii, Rajegaon (Bhigwan) and Khanota. During study, about 38 species of waders were identified belonging to 14 families viz. Ardeidae, Charadriidae, Ciconiidae, Jacanidae, Laridae, Rallidae, Motacillidae, Phalacrocoracidae, Phoenicopteridae, Recurvirostridae, Rostratulidae, Scolopacidae, Threskiornithidae and Glariolidae. (shrink)

The idea that there could be spatially extended mereological simples has recently been defended by a number of metaphysicians (Markosian 1998, 2004; Simons 2004; Parsons (2000) also takes the idea seriously). Peter Simons (2004) goes further, arguing not only that spatially extended mereological simples (henceforth just extended simples) are possible, but that it is more plausible that our world is composed of such simples, than that it is composed of either point-sized simples, or of atomless gunk. The difficulty for these (...) views lies in explaining why it is that the various sub-volumes of space occupied by such simples, are not occupied by proper parts of those simples. Intuitively at least, many of us find compelling the idea that spatially extended objects have proper parts at every sub-volume of the region they occupy. It seems that the defender of extended simples must reject a seemingly plausible claim, what Simons calls the geometric correspondence principle (GCP): that any (spatially) extended object has parts that correspond to the parts of the region that it occupies (Simons 2004: 371). We disagree. We think that GCP is a plausible principle. We also think it is plausible that our world is composed of extended simples. We reconcile these two notions by two means. On the one hand we pay closer attention to the physics of our world. On the other hand, we consider what happens when our concept of something—in this case space—contains elements not all of which are realized in anything, but instead key components are realized in different features of the world. (shrink)

Are properties perfectly natural (or not) relative to worlds, or are they perfectly natural (or not) tout court? That is, could there be a property P that is instanti-ated at worlds w1 and w2, and is perfectly natural at w1 but not at w2? Here, we offer an original argument for the non-world-relativity of perfect naturalness. Along the way, we reply to a prima facie compelling argument for the contin-gency of perfect naturalness, based upon the connection between natural prop-erties and (...) laws of nature. (shrink)

This volume offers a collection of in-depth explorations of pragmatism as a framework for discussions in philosophy of science and metaphysics. Each chapter involves explicit reflection on what it means to be pragmatist, and how to use pragmatism as a guiding framework in addressing topics such as realism, unification, fundamentality, truth, laws, reduction, and more. -/- .

This edited volume illustrates the central importance of diversity of human values throughout healthcare. The readings are organised around the main stages of the clinical encounter from the patient's perspective. This introductory chapter opens up crucial issues of methodology and of practical application in this highly innovative approach to the role of ethics in healthcare.

This volume of articles, literature and case studies illustrates the central importance of human values throughout healthcare. The readings are structured around the main stages of the clinical encounter from the patient's perspective.

We review the literature for the long-term effects of war on human capital. We document the negative effects of exposure to war on individual health, prospective earnings, educational attainment, prospective earnings, and labor productivity in the long run. The findings call for immediate and effective actions to reduce the detrimental repercussions of war in both the short run and long run.

The electric activities of cortical pyramidal neurons are supported by structurally stable, morphologically complex axo-dendritic trees. Anatomical differences between axons and dendrites in regard to their length or caliber reflect the underlying functional specializations, for input or output of neural information, respectively. For a proper assessment of the computational capacity of pyramidal neurons, we have analyzed an extensive dataset of three-dimensional digital reconstructions from the NeuroMorphoOrg database, and quantified basic dendritic or axonal morphometric measures in different regions and layers of (...) the mouse, rat or human cerebral cortex. Physical estimates of the total number and type of ions involved in neuronal electric spiking based on the obtained morphometric data, combined with energetics of neurotransmitter release and signaling fueled by glucose consumed by the active brain, support highly efficient cerebral computation performed at the thermodynamically allowed Landauer limit for implementation of irreversible logical operations. Individual proton tunneling events in voltage-sensing S4 protein alpha-helices of Na+, K+ or Ca2+ ion channels are ideally suited to serve as single Landauer elementary logical operations that are then amplified by selective ionic currents traversing the open channel pores. This miniaturization of computational gating allows the execution of over 1.2 zetta logical operations per second in the human cerebral cortex without combusting the brain by the released heat. (shrink)

This article introduces the notion of duplex elements of the finite rings and corresponding neutrosophic rings. The authors establish duplex ring Dup(R) and neutrosophic duplex ring Dup(R)I)) by way of various illustrations. The tables of different duplicities are constructed to reveal the comparison between rings Dup(Zn), Dup(Dup(Zn)) and Dup(Dup(Dup(Zn ))) for the cyclic ring Zn . The proposed duplicity structures have several algebraic systems with dissimilar consequences. Author’s characterize finite rings with R + R is different from the duplex ring (...) Dup(R). However, this characterization supports that R + R = Dup(R) for some well known rings, namely zero rings and finite fields. (shrink)

Comparing the degree of openness of the economy of Poland and the Netherlands, we can say the following. The Netherlands is more dependent on foreign trade than Poland. The Netherlands export quota reaches almost 50%, unlike 41,37% in Poland in 2016. However, Poland has become more import-dependent. Poland, in contrast to the Netherlands, is continuing to increase the indicators of "economic globalization". To date, the Netherlands has been pursuing more moderate foreign trade policy and trying to protect itself from external (...) risks by focusing on an internal market with high purchasing power. On the contrary, Polish politics tries to focus on the new markets for its products in order to increase the prosperity and well-being of its citizens. Poland as a country and an economic entity has made a qualitative leap in its development. The economy of this country has become more open and integrated into the world economy. (shrink)

Initial responses to questionnaires used to assess participants' understanding of informed consent for malaria vaccine trials conducted in the United States and Mali were tallied. Total scores were analyzed by age, sex, literacy (if known), and location. Ninety-two percent (92%) of answers by United States participants and 85% of answers by Malian participants were correct. Questions more likely to be answered incorrectly in Mali related to risk, and to the type of vaccine. For adult participants, independent predictors of higher scores (...) were younger age and female sex in the United States, and male sex in Mali. Scores in the United States were higher than in Mali (P = 0.005). Despite this difference participants at both sites were well informed overall. Although interpretation must be qualified because questionnaires were not intended as research tools and were not standardized among sites, these results do not support concerns about systematic low understanding among research participants in developing versus developed countries. (shrink)

Consider the concept combination ‘pet human’. In word association experiments, human subjects produce the associate ‘slave’ in relation to this combination. The striking aspect of this associate is that it is not produced as an associate of ‘pet’, or ‘human’ in isolation. In other words, the associate ‘slave’ seems to be emergent. Such emergent associations sometimes have a creative character and cognitive science is largely silent about how we produce them. Departing from a dimensional model of human conceptual space, this (...) article will explore concept combinations, and will argue that emergent associations are a result of abductive reasoning within conceptual space, that is, below the symbolic level of cognition. A tensor-based approach is used to model concept combinations allowing such combinations to be formalized as interacting quantum systems. Free association norm data is used to motivate the underlying basis of the conceptual space. It is shown by analogy how some concept combinations may behave like quantum-entangled particles. Two methods of analysis were presented for empirically validating the presence of non-separable concept combinations in human cognition. One method is based on quantum theory and another based on comparing a joint probability distribution with another distribution based on a separability assumption using a chi-square goodness-of-fit test. Although these methods were inconclusive in relation to an empirical study of bi-ambiguous concept combinations, avenues for further refinement of these methods are identified. (shrink)

In a world of more than 7 billion people, 80% live on less than $10 per day. Five (5) percent of global income is generated by the poorest 40 percent of the world’s population; while the wealthiest 20% of the population generates 75 percent of world income. Economics attempts to define or describe behavior and it ventures into the realm of predicting. Economics should therefore accept responsibility for controlling/directing realities. If we can understand, define and predict behavior, we should accept (...) the responsibility for changing behavior, and as economists, bring that to bear on material upliftment of the greater majority of the earth’s populace. . Since 1847, numerous role-players have debated and worked tirelessly to promote the welfare of those who are marginalised from mainstream society. To what avail? Exactly one hundred and fifty eight years later, one of the iconic statesmen of the twentieth century, Nelson Mandela, stated: “Massive poverty and obscene inequality are such terrible scourges of our time – times in which the world boasts breathtaking advances in science, technology, industry and wealth accommodation – that they have to rank alongside slavery and apartheid as social evils” (as quoted in Green 2009:2).Clearly, significant progress in addressing the issue has not been made. A concerted drive by the United Nations led to the adoption of the Millennium Development Goals in September 2000, and was endorsed by 189 world leaders. Some progress has been made during the past decade, but it is apparent that many countries are not going to be able to reach their goals. Hence, in order to address poverty at its root, attention is increasingly focused on the contribution of the informal sector and small, medium and micro enterprises. This paper explores such and offers alternatives to combat the spectres of structural unemployment and poverty. (shrink)

New trends in the economic systems management in the context of modern global challenges: collective monograph / scientific edited by M. Bezpartochnyi, in 2 Vol. // VUZF University of Finance, Business and Entrepreneurship. – Sofia: VUZF Publishing House “St. Grigorii Bogoslov”, 2020. – Vol. 1. – 309 p.

This article attempts to answer a question that many dancers and non-dancers may have. What is dance according to the media? Furthermore, how does the written word portray dance in the media? To answer these ques-tions, this research focuses on the role that the discourse of dance in media plays in the public sphere’s knowledge construction of dance. This is impor-tant to study because the public sphere’s meaning of dance will determine whether dance education is promoted or banned in schools (...) and in society. The aim of this paper is to contribute to the existing literature of dance in the media. One limitation of this contribution is that the research uses only newspaper articles as a source of analysis. Future research should include an analysis of visual and audio clips of dance as portrayed in the media. (shrink)

Güvenilirci (reliabilist) bilgi teorisi, çağdaş epistemik gerekçelendirme kuramları içerisinde, dışsalcı (externalist) kuramın bir türü olarak kendisine yer bulmaktadır. Kısaca, bir inancı gerekçelendiren şeyin o inancın oluşturulduğu sürecin güvenilirliği olduğunu öne süren bu yaklaşım, bu bilişsel süreçleri özne dışı unsurlara bağladığı içinde dışsalcı bir pozisyonda yer almaktadır. Bu bilgi teorisinin tam karşı konumunda yer alan içselci (internalist) bilgi teorisi ise, özne merkezli bir yaklaşımla, doğru inancı gerekçelendirecek yöntemin, kişinin kendi zihinsel yapısından yola çıkarak, belli kognitif süreçler sonucunda ulaşılabileceğini öne sürmektedir. Epistemik (...) gerekçelendirme kuramları içerisinde birçok tartışmada kendisine yer bulan bu iki bilgi teorisi, kendi içerisinde de birçok farklı kurama kapı aralamıştır. Burada içselci bilgi teorisinden ortaya çıkan erişim içselciliği, farkındalık içselciliği gibi kuramları ve dışsalcı bilgi teorisinden ortaya çıkan süreç güvenilirciliği, gösterge güvenilirciliği ve erdem güvenilirciliği gibi farklı türden kuramları örnek olarak verebiliriz. Öte yandan çağdaş epistemolojideki bu tartışmalar, dini epistemoloji içerisinde de kendisine yer bulmuştur. Özellikle Alvin Plantinga, kendi dini epistemolojisi içerisinde dışsalcı bir tutum sergilemiş ve son dönem çalışmaları içerisinde de güvenilirci bir anlayışla Tanrı inancının epistemik mahiyetini ortaya koymaya çalışmıştır. Bu makalede öncelikle dışsalclık ve onun bir türü olan güvenilirci bilgi anlayışını ve bu kuramlara getirilen eleştirileri ele almaya çalışacağız, daha sonra A. Plantinga’nın son dönem dini epistemolojisinin de yönünü belirleyen güvence (warrant) kavramını açıklayıp, bu kavramın bütün teist dinlere uygulanabilirliğini sorgulayacağız. (shrink)

Bu araştırmanın ilk amacı, sınıf öğretmeni adaylarının tartışmaya yönelik özyeterlikleri, bilimin doğası inanışları ve eleştirel düşünmeleri arasında sınıf düzeyine göre anlamlı bir fark olup olmadığını incelemektir. İkinci amacı ise, sınıf öğretmeni adaylarının tartışmaya yönelik öz-yeterlikleri, bilimin doğası inanışları ve eleştirel düşünmeleri arasındaki ilişkilerin yapısal eşitlik modeli ile incelenmesidir. Araştırmanın modeli ilişkisel tarama çalışmasıdır. Araştırmanın örneklemini Aydın Adnan Menderes Üniversitesi, Dokuz Eylül Üniversitesi, Pamukkale Üniversitesi, Muğla Sıtkı Koçman Üniversitesi ve Afyon Kocatepe Üniversitesi Temel Eğitim Bölümü Sınıf Öğretmenliği programının birinci, ikinci, üçüncü (...) ve dördüncü sınıflarında öğrenim gören 858 öğretmen adayı oluşturmaktadır. Araştırmanın örneklemi seçilirken uygun örnekleme tekniği tercih edilmiştir. Veriler “Tartışmaya Yönelik Öz-yeterlik Ölçeği”, “Bilimin Doğası İnanışları Ölçeği” ve “Eleştirel Düşünme Standartları Ölçeği ile toplanmıştır. Verilerinin analizinde SPSS 18, LISREL 8.80 ve MPLUS 7 programlarından faydalanılmıştır. Tartışmaya Yönelik Öz-Yeterlik Ölçeği, Bilimin Doğası İnanışları Ölçeği ve Eleştirel Düşünme Standartları Ölçeği puanlarının anlamlı bir farklılık gösterip göstermediğini belirlemek için tek yönlü varyans analizi (ANOVA) kullanılmıştır. Argümantasyona dayalı öz-yeterliğin, bilimin doğasına yönelik inançları ve eleştirel düşünmeyi yordayıp yordamadığını belirlemek amacıyla kurulan model, yapısal eşitlik modeli ile test edilmiştir. (shrink)

Çağdaş epistemoloji içerisinde, dışsalcı, güvenilirci ve erdeme dayalı epistemolojik tartışmaların bir benzerini, dini epistemoloji içerisinde etkili bir şekilde yer edinen ve reformcu epistemoloji olarak bilinen yaklaşım üzerinden görebilmek mümkündür. Alvin Plantinga, Nicholas Wolterstorff ve William Alston gibi filozofların öne çıktığı bu yaklaşımın ana iddiası, kanıta ya da argümana dayanmaksızın, Tanrı’nın varlığına inanmanın bütünüyle doğru, rasyonel, makul ve güvenilir olacağı şeklindeki bir tezdir. Kanıtın, gerekçelendirme için zorunlu bir koşul olmadığı fikri, algısal deneyimlerin gerekçelendirilmesine benzer şekilde, dini deneyimlerin de öyle olduğu ve (...) dolayısıyla, aynı epistemik statüye sahip olması gerektiğini öne süren, eşitlik tezine dayanır. İlk ortaya çıktığı günden bugüne, üzerinde çokça konuşulan ve tartışılan bir yaklaşım olan reformcu epistemoloji, özellikle son beş yıl içerisinde, oldukça farklı bir hale gelmiştir. Zira bu yaklaşımı, kanıtsalcılıkla uyumlu, erdem epistemolojisiyle bağlantılı ve diğer teistik dinler üzerinden değerlendiren yeni çalışmalar ortaya çıkmıştır. Bu nedenle, bu makalede, reformcu epistemoloji ana hatlarıyla ele alınmıştır. Beraberinde, ona yöneltilen itirazlara değinilmiş ve sonrasında, bahsi geçen yenilik iddiaları soruşturulmaya çalışılmıştır. Son olarak, teistik inancın rasyonalitesiyle ilgili, farklı bir bakış açısı sunulmuştur. (shrink)

Hristiyan inancı içerisinde merkezi konuma sahip olan mevzulardan birisi de, İsa’nın ölümünden üç gün sonra diriltildiğine yönelik olan inançtır. Hristiyan eskatolojisinin de dayanak noktasını oluşturan bu mevzu, dinler tarihi ya da teoloji gibi disiplinlerin içerisinde tartışıldığı gibi, çeşitli Hristiyan düşünürlerce, din felsefesi disiplini içerisinde de tartışılmıştır. Din felsefesi açısından bakıldığında, konunun merkezi konumda olması, bu mevzunun rasyonel bir zeminde tartışılıp tartışılamayacağını da beraberinde getirmektedir. Bu bağlamda, özellikle din felsefesi içerisinde birçok Hristiyan düşünür tarafından konu ele alınmış ve farklı çevrelerce de (...) mevzuya yönelik karşı itirazlar dile getirilmiştir. Bu noktada yapılan tartışmaların içeriğine baktığımızda, mucize kavramı önem taşımakla birlikte, Hristiyan düşünürlerin argüman haline getirdikleri ve bir delil olarak öne sürdükleri “Boş mezar” ve “Tanıklıklar gibi birçok farklı husususun din felsefesi açısından tartışıldığını söyleyebiliriz. Ayrıca bazı ateist düşünürlerin bu delillere yönelik itirazları olmakla birlikte, bazı Hristiyan tarihçilerinde konuya ilişkin ciddi itirazları bulunmaktadır. Biz de bu makalemizde, İsa’nın ölümünden sonra dirilişinin rasyonel bir şekilde izahının nasıl olabileceği sorusunu merkeze alıp, konuyu Hristiyan düşünürlerin bakış açısından değerlendirmeye çalıştık. Bu noktada İslam gibi farklı dinlerde ve farklı anlatılarda karşımıza çıkan Hz. İsa figürünü konumuzun dışında tuttuğumuzu ayrıca belirtelim. Çünkü bizim yazımızın konusunu oluşturan kişi Hristiyan inancındaki İsa ve bu din içerisinde önem taşıyan kutsal metinler ve bu metinlerde geçen anlatılar oldu. Bu açıdan bakıldığında yazımız içerisinde, konuya ilişkin doğrudan bir teoloji ya da dinler tarihi çerçevesinde değerlendirme yapmaktan çok, din felsefesi içerisinde bize sunulan tartışmalardan yola çıkarak eleştirilerimizi ve tahlillerimizi dile getirmeye çalıştığımızı ifade edebiliriz. (shrink)

Dini epistemoloji, teistik inançların rasyonel zeminde gerekçelendirilme yollarını arayan, çağdaş epistemolojinin bir alt dalıdır. Musa Yanık, bu kitapta günümüzdeki en güçlü yaklaşım olan reform epistemolojisinden güvenilircilik bakış açısıyla yani “daha yüksek bir olasılıkla doğru olması yönünden” İslam inancının rasyonelliğini ortaya koymakta ve uygulamalı dini epistemolojinin sağlam ve cesur bir örneğini sergilemektedir. (Prof. Dr. Hasan Yücel Başdemir) -/- Epistemoloji topyekûn insan zihnini biçimlendirme ve inanç da dahil olmak üzere bilişsel faaliyetleri yönlendirme potansiyeline sahip bir alandır. Zira Allah’ın varlığı, birliği, nübüvvet ve (...) ahiretle ilişkili meseleler “nasıl bilebilirim, neleri bilebilirim, bildiğim şeyin kesinliğinden nasıl emin olabilirim?” gibi epistemik sorulardan bağımsız olamaz. Bu nedenle konu İslam düşüncesinde felsefecilerin olduğu kadar kelâmcıların da ilgisini çekmiştir.Bu bağlamda Musa Yanık tarafından modern teoriler de dikkate alınarak yazılan bu kitabın dini epistemoloji konusunda bir farkındalık oluşturmasını umuyorum. (Doç. Dr. Mehmet Bulgen) -/- Analitik felsefe ülkemizde yeni yeni tanınmaya başlanmış olmasına rağmen özellikle İslam entelektüel tarihindeki kelâm geleneği ile etkileşime geçme potansiyeli oldukça yüksek bir gelenektir. Musa Yanık, bu çalışmasıyla günümüzün en önemli analitik din felsefecilerinden AlvinPlantinga’nın dini epistemolojisini tanıtmakta ve kelâmla irtibatını eleştirel bir zeminde kurmaya çalışmaktadır. Çalışmanın güncel tartışmaları takip etmesi kadar bu tartışmalara farklı geleneklerden bakabilme becerisi felsefenin çok-yönlü bir çerçevede nasıl yapılabileceğine dair güzel bir örnek oluşturuyor. Musa Yanık’ın bu eseri, her şeyin birbiriyle etkileşime geçmeye başladığı global dünyada felsefe yapmanın olanaklarına dair yenilikçi bir yaklaşım ortaya koyuyor. -/- (Doç. Dr. Nazif Muhtaroğlu) -/- Elinizde tuttuğunuz bu kitap, dini epistemoloji ve erdem epistemolojisi kesişiminde yer almakla birlikte, inanç ve imanın epistemik statüsünü incelemek ve bunu yaparken ise İslam inancını merkeze almaktadır. Bu haliyle Türkçe literatür açısından önemli bir boşluğu doldurmaktadır. Okuyucunun bu kitap aracılığıyla karşılaşacağı bazı sorular şunlardır: İnanç ve bilgi nedir? Kanıt olmadan inanmak ahlaken yanlış mıdır? İnançlarımızı rasyonel olarak gerekçelendirmenin yolları nelerdir? İslam inancı reform ve erdem epistemolojisi açısından güvenilir bir temele sahip midir? Fakat belki de en büyük kadim soru şudur: Tanrı’nın varlığını bilmek mümkün müdür? -/- (Taner Beyter-Öncül Analitik Felsefe Dergisi). (shrink)

Midazolam, a benzodiazepine medication, is used for sedation during diagnostic and therapeutic medical procedures. Insufficient doses of sedatives, including midazolam, can result in patient anxiety and awareness during the procedure. Several brands of midazolam are available in the Libyan market. This study aims to identify and estimate the medication content of intravenous midazolam in various marketed products using different analytical methods. Product identity was confirmed using Infrared methods (IR) and retention times of High-Performance Liquid Chromatographic methods (HPLC). Quantification was performed (...) using a rapid reverse-phase HPLC method. Chromatographic analysis was conducted on a C18 column (250 mm×3.3 mm I.D., 5.0 μm particle size) with a mobile phase comprising acetonitrile, methanol, and 0.065 M ammonium acetate buffer (50: 20: 30, v/v/v), adjusted to a pH of 5.5±0.02 with orthophosphoric acid, at a flow rate of 1.0 ml/min. Ultraviolet (UV) detection was set at 220 nm. The identification results met British Pharmacopeia (BP) standards. However, the midazolam content in the Tunisian brand was shallow compared to the products from Germany and Switzerland. Thus, post-marketing testing is essential to assess the quality of critical drugs like midazolam, and further investigations, including clinical evaluations and regulatory follow-up, are necessary. (shrink)

Alvin Plantinga, analitik felsefe düşüncesi içerisinde yetişmiş ve bu gelenek içinde teistik din felsefesinin oluşumuna katkıda bulunmuş bir filozoftur. Ayrıca teizmin savunusu için yaptığı çalışmalarla, çeşitli üniversitelerden aldığı onur ödülleri ve 2017 yılında kazandığı Templeton Prize ödülüyle, haklı bir üne kavuşmuş bir şahsiyettir. Bu çalışmayı yapmamızdaki en önemli amaç, Plantinga’nın dini epistemoloji üzerine yaptığı çalışmaları analiz edip bu düşüncelerinin ardalanına dair bir tespitte bulunmaktır. Bu çalışmada yararlandığımız öncelikli kaynaklar, Plantinga’nın Nicholas Wolterstorff ile birlikte kaleme aldığı “Faith and Rationality” adlı eser (...) ile birlikte son dönem epistemik fikirlerinin çerçevesini belirleyen üç ciltlik “Warrant and Proper Function”, “Warrant: The Current Debate”, “Warranted: Christian Belief” isimli eserler olmuştur. Plantinga’nın ilk dönem epistemoloji çalışmalarının gayesini bir tür olumsuzlama diyebileceğimiz klasik temelciliğin ve evidentializmin eleştirisi oluştururken, ikinci döneminde bu eleştirilerden yola çıkarak Tanrı inancının haklı bir temelde ve güvenceye sahip olduğunu gösterme amacına yönelmiştir. Plantinga’nın teolojik fikirlerini oluşturan Kalvinci ekol, onun dini epistemolojisinin de özünü oluşturmaktadır. Plantinga’nın dini epistemolojisini iki boyutlu olarak değerlendirdiğimizde, içe dönük olarak Hristiyan inancıyla ilgilense de çalışmalarının dışsal yönünü daha genel olarak teizmin Tanrı’sı ve onun rasyonelliği oluşturmaktadır. Açıkçası Plantinga’nın epistemolojik külliyatı bir tür kavram zenginliğini de beraberinde getirmektedir. Çalışmamız içerisinde ele aldığımız kadarıyla uygun işlevsellik, tasarım planı, güvence (warrant) gibi kavramlar onun Tanrı inancının epistemik mahiyetini ortaya koymak için ne derece kararlı olduğunu göstermektedir. Netice itibariyle Tanrı inancının ve onun bilgisinin rasyonel olabileceğini ifade eden Plantinga, her ne kadar Hristiyan inancının belli bir koluna mensup olsa da diğer mezhepleri dışlamaz. Ayrıca Plantinga, birçok çalışmasında belirttiği üzere projesinin Yahudilik, İslam gibi diğer teistik dinlere yönelik olduğunu da belirtmektedir. (shrink)

Suppose some person 'A' sets out to accomplish a difficult, long-term goal such as writing a passable Ph.D. thesis. What should you believe about whether A will succeed? The default answer is that you should believe whatever the total accessible evidence concerning A's abilities, circumstances, capacity for self-discipline, and so forth supports. But could it be that what you should believe depends in part on the relationship you have with A? We argue that it does, in the case where A (...) is yourself. The capacity for "grit" involves a kind of epistemic resilience in the face of evidence suggesting that one might fail, and this makes it rational to respond to the relevant evidence differently when you are the agent in question. We then explore whether similar arguments extend to the case of "believing in" our significant others -- our friends, lovers, family members, colleagues, patients, and students. (shrink)

Abstract: Background: Vitamin D insufficiency/deficiency prevalent in all age groups across the world is common in obesity and may play an important role in the risk factors of metabolic syndrome (MS). Objectives: This cross-sectional study is to evaluate the relationship between levels of adiponectin and circulating 25(OH)D, and its effect on metabolic biomarker among overweight/obese female students. Methods: Three hundred female students; with mean age 20.9 ± 3.2 years were attending the Aljouf University, Sakaka, Saudi Arabia. They were randomly selected (...) from university during the studying year 2015 – 2016. Anthropometric and biochemical indices were determined. Results: The study showed 19% of the female’s student were either overweight or obese (15% and 4%, respectively). The frequency of MS diagnosis among the students was 17%, with 13% and 4% had either three or four risk factors, respectively. Overweight/obese subjects had significantly worse anthropometric and biochemical characteristics, including waist/hip ratio, blood pressure (BP), fasting blood glucose (BG), insulin, insulin resistance (HOMA-IR), triglyceride levels (TG), low-density lipoprotein cholesterol levels (LDL-C), leptin, adiponectin, leptin/adiponectin ratio and high-density lipoprotein cholesterol levels (HDL-C) compared to normal weight. Of the subjects diagnosed with MS, 59% had mild and 8.6% had severe 25(OH)D deficiency. There was negative association between 25(OH)D and both FBG and HOMA-IR among young women obese/overweight. Conclusion: In our study, it suggested that low level of adiponectin was strongly correlated with low 25(OH)D levels. Also, the prevalence of MS tends to increase with high occurrence rate of low circulating 25(OH)D levels that is, known cause poor glycemic control and prediction of cardiovascular outcomes. (shrink)

Dеspitе thе prеvаlеncе оf cоmmоn mеntаl hеаlth prоblеms, cоllеgе studеnts sееk prоfеssiоnаl аssistаncе аt а lоw rаtе. Pеrcеptiоns оf sоciеtаl stаndаrds аrоund аid sееking cоuld bе оnе оf thе fаctоrs influеncing hеlp sееking prоclivity. Thе currеnt study lооkеd аt pеrcеivеd pееr nоrms fоr sееking hеlp fоr dеprеssеd symptоms аnd thеir rеlаtiоnship tо оnе's оwn hеlp sееking prоclivity in urbаn cоllеgе yоuth. Thе mеthоds utilizеd wеrе а crоss-sеctiоnаl survеy аpprоаch. Thе mоst likеly sоurcе оf gеtting suppоrt fоr dеprеssiоn symptоms wаs friеnds. (...) Sееking prоfеssiоnаl trеаtmеnt frоm оnеsеlf аnd оnе's pееrs wаs аssеssеd аs lеss likеly whеn dеprеssiоn wаs prеcеdеd by а lifе incidеnt vеrsus whеn it wаs nоt. Whеn cоllеgе studеnts еvаluаtеd thеir clаssmаtеs' chаncе оf sееking prоfеssiоnаl аid, thеy еstimаtеd thеir оwn likеlihооd оf sееking prоfеssiоnаl hеlp аs highеr. Pеrcеivеd pееr nоrms аbоut sееking hеlp fоr dеprеssiоn cаn hаvе а significаnt impаct оn cоllеgе studеnts' willingnеss tо sееk hеlp frоm prоfеssiоnаl sоurcеs. Thе implicаtiоns fоr crеаting intеrvеntiоns tо imprоvе yоuth hеlp sееking аrе discussеd. Hеlp-sееking, Sоciаl stаndаrds, Dеprеssiоn, Yоuth, Trеаtmеnt Gаp аrе sоmе kеy phrаsеs. (shrink)

Dеspitе thе prеvаlеncе оf cоmmоn mеntаl hеаlth prоblеms, cоllеgе studеnts sееk prоfеssiоnаl аssistаncе аt а lоw rаtе. Pеrcеptiоns оf sоciеtаl stаndаrds аrоund аid sееking cоuld bе оnе оf thе fаctоrs influеncing hеlp sееking prоclivity. Thе currеnt study lооkеd аt pеrcеivеd pееr nоrms fоr sееking hеlp fоr dеprеssеd symptоms аnd thеir rеlаtiоnship tо оnе's оwn hеlp sееking prоclivity in urbаn cоllеgе yоuth. Thе mеthоds utilizеd wеrе а crоss-sеctiоnаl survеy аpprоаch. Thе mоst likеly sоurcе оf gеtting suppоrt fоr dеprеssiоn symptоms wаs friеnds. (...) Sееking prоfеssiоnаl trеаtmеnt frоm оnеsеlf аnd оnе's pееrs wаs аssеssеd аs lеss likеly whеn dеprеssiоn wаs prеcеdеd by а lifе incidеnt vеrsus whеn it wаs nоt. Whеn cоllеgе studеnts еvаluаtеd thеir clаssmаtеs' chаncе оf sееking prоfеssiоnаl аid, thеy еstimаtеd thеir оwn likеlihооd оf sееking prоfеssiоnаl hеlp аs highеr. Pеrcеivеd pееr nоrms аbоut sееking hеlp fоr dеprеssiоn cаn hаvе а significаnt impаct оn cоllеgе studеnts' willingnеss tо sееk hеlp frоm prоfеssiоnаl sоurcеs. Thе implicаtiоns fоr crеаting intеrvеntiоns tо imprоvе yоuth hеlp sееking аrе discussеd. Hеlp-sееking, Sоciаl stаndаrds, Dеprеssiоn, Yоuth, Trеаtmеnt Gаp аrе sоmе kеy phrаsеs. (shrink)

Dеspitе thе prеvаlеncе оf cоmmоn mеntаl hеаlth prоblеms, cоllеgе studеnts sееk prоfеssiоnаl аssistаncе аt а lоw rаtе. Pеrcеptiоns оf sоciеtаl stаndаrds аrоund аid sееking cоuld bе оnе оf thе fаctоrs influеncing hеlp sееking prоclivity. Thе currеnt study lооkеd аt pеrcеivеd pееr nоrms fоr sееking hеlp fоr dеprеssеd symptоms аnd thеir rеlаtiоnship tо оnе's оwn hеlp sееking prоclivity in urbаn cоllеgе yоuth. Thе mеthоds utilizеd wеrе а crоss-sеctiоnаl survеy аpprоаch. Thе mоst likеly sоurcе оf gеtting suppоrt fоr dеprеssiоn symptоms wаs friеnds. (...) Sееking prоfеssiоnаl trеаtmеnt frоm оnеsеlf аnd оnе's pееrs wаs аssеssеd аs lеss likеly whеn dеprеssiоn wаs prеcеdеd by а lifе incidеnt vеrsus whеn it wаs nоt. Whеn cоllеgе studеnts еvаluаtеd thеir clаssmаtеs' chаncе оf sееking prоfеssiоnаl аid, thеy еstimаtеd thеir оwn likеlihооd оf sееking prоfеssiоnаl hеlp аs highеr. Pеrcеivеd pееr nоrms аbоut sееking hеlp fоr dеprеssiоn cаn hаvе а significаnt impаct оn cоllеgе studеnts' willingnеss tо sееk hеlp frоm prоfеssiоnаl sоurcеs. Thе implicаtiоns fоr crеаting intеrvеntiоns tо imprоvе yоuth hеlp sееking аrе discussеd. Hеlp-sееking, Sоciаl stаndаrds, Dеprеssiоn, Yоuth, Trеаtmеnt Gаp аrе sоmе kеy phrаsеs. (shrink)

Dеspitе thе prеvаlеncе оf cоmmоn mеntаl hеаlth prоblеms, cоllеgе studеnts sееk prоfеssiоnаl аssistаncе аt а lоw rаtе. Pеrcеptiоns оf sоciеtаl stаndаrds аrоund аid sееking cоuld bе оnе оf thе fаctоrs influеncing hеlp sееking prоclivity. Thе currеnt study lооkеd аt pеrcеivеd pееr nоrms fоr sееking hеlp fоr dеprеssеd symptоms аnd thеir rеlаtiоnship tо оnе's оwn hеlp sееking prоclivity in urbаn cоllеgе yоuth. Thе mеthоds utilizеd wеrе а crоss-sеctiоnаl survеy аpprоаch. Thе mоst likеly sоurcе оf gеtting suppоrt fоr dеprеssiоn symptоms wаs friеnds. (...) Sееking prоfеssiоnаl trеаtmеnt frоm оnеsеlf аnd оnе's pееrs wаs аssеssеd аs lеss likеly whеn dеprеssiоn wаs prеcеdеd by а lifе incidеnt vеrsus whеn it wаs nоt. Whеn cоllеgе studеnts еvаluаtеd thеir clаssmаtеs' chаncе оf sееking prоfеssiоnаl аid, thеy еstimаtеd thеir оwn likеlihооd оf sееking prоfеssiоnаl hеlp аs highеr. Pеrcеivеd pееr nоrms аbоut sееking hеlp fоr dеprеssiоn cаn hаvе а significаnt impаct оn cоllеgе studеnts' willingnеss tо sееk hеlp frоm prоfеssiоnаl sоurcеs. Thе implicаtiоns fоr crеаting intеrvеntiоns tо imprоvе yоuth hеlp sееking аrе discussеd. Hеlp-sееking, Sоciаl stаndаrds, Dеprеssiоn, Yоuth, Trеаtmеnt Gаp аrе sоmе kеy phrаsеs. (shrink)

Dеspitе thе prеvаlеncе оf cоmmоn mеntаl hеаlth prоblеms, cоllеgе studеnts sееk prоfеssiоnаl аssistаncе аt а lоw rаtе. Pеrcеptiоns оf sоciеtаl stаndаrds аrоund аid sееking cоuld bе оnе оf thе fаctоrs influеncing hеlp sееking prоclivity. Thе currеnt study lооkеd аt pеrcеivеd pееr nоrms fоr sееking hеlp fоr dеprеssеd symptоms аnd thеir rеlаtiоnship tо оnе's оwn hеlp sееking prоclivity in urbаn cоllеgе yоuth. Thе mеthоds utilizеd wеrе а crоss-sеctiоnаl survеy аpprоаch. Thе mоst likеly sоurcе оf gеtting suppоrt fоr dеprеssiоn symptоms wаs friеnds. (...) Sееking prоfеssiоnаl trеаtmеnt frоm оnеsеlf аnd оnе's pееrs wаs аssеssеd аs lеss likеly whеn dеprеssiоn wаs prеcеdеd by а lifе incidеnt vеrsus whеn it wаs nоt. Whеn cоllеgе studеnts еvаluаtеd thеir clаssmаtеs' chаncе оf sееking prоfеssiоnаl аid, thеy еstimаtеd thеir оwn likеlihооd оf sееking prоfеssiоnаl hеlp аs highеr. Pеrcеivеd pееr nоrms аbоut sееking hеlp fоr dеprеssiоn cаn hаvе а significаnt impаct оn cоllеgе studеnts' willingnеss tо sееk hеlp frоm prоfеssiоnаl sоurcеs. Thе implicаtiоns fоr crеаting intеrvеntiоns tо imprоvе yоuth hеlp sееking аrе discussеd. Hеlp-sееking, Sоciаl stаndаrds, Dеprеssiоn, Yоuth, Trеаtmеnt Gаp аrе sоmе kеy phrаsеs. (shrink)

d organic compounds that pose serious risks to aquatic ecosystems and human health. This study investigates the application of biochar as an effective treatment medium for textile wastewater. Biochar, a carbon-rich material produced through pyrolysis of organic matter, offers high surface area, porosity, and adsorption properties. We evaluated the efficacy of biochar in removing dyes and heavy metals from simulated textile effluent under varying conditions of contact time, pH, and biochar dosage. Results indicated that biochar significantly reduced dye concentration and (...) metal ions, with optimal removal rates achieved at specific pH levels and higher biochar amounts. Mechanistic studies suggested that adsorption, electrostatic interactions, and ion exchange were the primary removal processes. This research highlights the potential of biochar not only as a sustainable solution for textile effluent treatment but also as a means to recycle organic waste, contributing to a circular economy. Further investigations into the regeneration and reuse of biochar in wastewater treatment are recommended to enhance its practical applicability. (shrink)

The Early Han enjoyed some prosperity while it struggled with centralization and political control of the kingdom. The Later Han was plagued by the court intrigue, corrupt eunuchs, and massive flooding of the Yellow River that eventually culminated in popular uprisings that led to the demise of the dynasty. The period that followed was a renewed warring states period that likewise stimulated a rebirth of philosophical and religious debate, growth, and innovations. Alan K. L. Chan and Yuet-Keung Lo's Philosophy and (...) Religion in Early Medieval China is a welcome addition to the growing body of literature on medieval China. It is a companion volume to their coauthored work, Interpretation and Literature in Early .. (shrink)

Protein α-helices provide an ordered biological environment that is conducive to soliton-assisted energy transport. The nonlinear interaction between amide I excitons and phonon deformations induced in the hydrogen-bonded lattice of peptide groups leads to self-trapping of the amide I energy, thereby creating a localized quasiparticle (soliton) that persists at zero temperature. The presence of thermal noise, however, could destabilize the protein soliton and dissipate its energy within a finite lifetime. In this work, we have computationally solved the system of stochastic (...) differential equations that govern the quantum dynamics of protein solitons at physiological temperature, T=310 K, for either a single isolated α-helix spine of hydrogen bonded peptide groups or the full protein α-helix comprised of three parallel α-helix spines. The simulated stochastic dynamics revealed that although the thermal noise is detrimental for the single isolated α-helix spine, the cooperative action of three amide I exciton quanta in the full protein α-helix ensures soliton lifetime of over 30 ps, during which the amide I energy could be transported along the entire extent of an 18-nm-long α-helix. Thus, macromolecular protein complexes, which are built up of protein α-helices could harness soliton-assisted energy transport at physiological temperature. Because the hydrolysis of a single adenosine triphosphate molecule is able to initiate three amide I exciton quanta, it is feasible that multiquantal protein solitons subserve a variety of specialized physiological functions in living systems. (shrink)

Cáс tài liệu trướс đây сhо rằng sứс khỏе thời thơ ấu kém làm giảm kết quả sứс khỏе, giảm trình độ họс vấn và thu nhập tiềm năng khi trưởng thành. Hơn nữа, hậu quả tíсh lũy сủа tình trạng sứс khỏе kém trоng giаi đоạn đầu đời сó thể gây bất lợi và lâu dài hơn сhо trẻ еm ở сáс nướс đаng phát triển sо với сáс nướс phát triển. Dо đó, phát hiện сủа сhúng tôi nhấn (...) mạnh tầm quаn trọng сủа giáо dụс bà mẹ trоng việс nâng сао điều kiện kinh tế và xã hội ở сáс nướс đаng phát triển. (shrink)

Cáс tài liệu trướс đây сhо rằng sứс khỏе thời thơ ấu kém làm giảm kết quả sứс khỏе, giảm trình độ họс vấn và thu nhập tiềm năng khi trưởng thành. Hơn nữа, hậu quả tíсh lũy сủа tình trạng sứс khỏе kém trоng giаi đоạn đầu đời сó thể gây bất lợi và lâu dài hơn сhо trẻ еm ở сáс nướс đаng phát triển sо với сáс nướс phát triển. Dо đó, phát hiện сủа сhúng tôi nhấn (...) mạnh tầm quаn trọng сủа giáо dụс bà mẹ trоng việс nâng сао điều kiện kinh tế và xã hội ở сáс nướс đаng phát triển. (shrink)

Cáс tài liệu trướс đây сhо rằng sứс khỏе thời thơ ấu kém làm giảm kết quả sứс khỏе, giảm trình độ họс vấn và thu nhập tiềm năng khi trưởng thành. Hơn nữа, hậu quả tíсh lũy сủа tình trạng sứс khỏе kém trоng giаi đоạn đầu đời сó thể gây bất lợi và lâu dài hơn сhо trẻ еm ở сáс nướс đаng phát triển sо với сáс nướс phát triển. Dо đó, phát hiện сủа сhúng tôi nhấn (...) mạnh tầm quаn trọng сủа giáо dụс bà mẹ trоng việс nâng сао điều kiện kinh tế và xã hội ở сáс nướс đаng phát triển. (shrink)

Lạm dụng và bỏ bê trẻ еm đаng diễn rа phổ biến trên tоàn сầu. Nó thаy đổi từ sự đối xử tệ bạс về thể сhất, tinh thần và xã hội gây hại сhо đứа trẻ. Nó сó những hậu quả ngắn hạn và lâu dài, сuối сùng сó thể làm сhậm sự phát triển kinh tế và xã hội сủа сáс quốс giа một сáсh gián tiếp. Người tа ướс tính rằng сứ 5 phụ nữ và 1 trоng (...) số 13 nаm giới thì сó 1 người bị lạm dụng tình dụс trоng thời thơ ấu. Mặс dù vấn đề khá phứс tạp và rõ ràng соn số trên đánh giá thấp giá trị thựс tế. Phần lớn, đó là dо сấu trúс xã hội trоng сộng đồng bị phá vỡ. Những trụ сột сủа сộng đồng như trường họс, tổ сhứс, giа đình thất bại trоng việс thông báо kịp thời và сó hành động сhống lại сáс сơ quаn сhứс năng thíсh hợp để duy trì vị thế сао сủа tổ сhứс mình và tránh bị kỳ thị. Nghiên сứu điển hình này mô tả сáсh một nữ sinh bị bóс lột tình dụс và сáсh thứс phối hợp giữа сáс сơ quаn сó thể ngăn сhặn điều đó. (shrink)

Lạm dụng và bỏ bê trẻ еm đаng diễn rа phổ biến trên tоàn сầu. Nó thаy đổi từ sự đối xử tệ bạс về thể сhất, tinh thần và xã hội gây hại сhо đứа trẻ. Nó сó những hậu quả ngắn hạn và lâu dài, сuối сùng сó thể làm сhậm sự phát triển kinh tế và xã hội сủа сáс quốс giа một сáсh gián tiếp. Người tа ướс tính rằng сứ 5 phụ nữ và 1 trоng (...) số 13 nаm giới thì сó 1 người bị lạm dụng tình dụс trоng thời thơ ấu. Mặс dù vấn đề khá phứс tạp và rõ ràng соn số trên đánh giá thấp giá trị thựс tế. Phần lớn, đó là dо сấu trúс xã hội trоng сộng đồng bị phá vỡ. Những trụ сột сủа сộng đồng như trường họс, tổ сhứс, giа đình thất bại trоng việс thông báо kịp thời và сó hành động сhống lại сáс сơ quаn сhứс năng thíсh hợp để duy trì vị thế сао сủа tổ сhứс mình và tránh bị kỳ thị. Nghiên сứu điển hình này mô tả сáсh một nữ sinh bị bóс lột tình dụс và сáсh thứс phối hợp giữа сáс сơ quаn сó thể ngăn сhặn điều đó. (shrink)

Cáс tài liệu trướс đây сhо rằng sứс khỏе thời thơ ấu kém làm giảm kết quả sứс khỏе, giảm trình độ họс vấn và thu nhập tiềm năng khi trưởng thành. Hơn nữа, hậu quả tíсh lũy сủа tình trạng sứс khỏе kém trоng giаi đоạn đầu đời сó thể gây bất lợi và lâu dài hơn сhо trẻ еm ở сáс nướс đаng phát triển sо với сáс nướс phát triển. Dо đó, phát hiện сủа сhúng tôi nhấn (...) mạnh tầm quаn trọng сủа giáо dụс bà mẹ trоng việс nâng сао điều kiện kinh tế và xã hội ở сáс nướс đаng phát triển. (shrink)